Collateral Therapeutics approached us to design its first annual report. They wanted to explore the emotional effects of their product, which is a gene therapy and delivery system for cardiovascular disease. By focusing on the mind-boggling statistics of heart disease, we were able to put a face to the problem and gain the empathy and interest of the reader. Exercises of comparison through multiple series of photographs reveal the potential benefits of gene therapy as a better alternative to existing models of surgery and drug therapy.